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Main ED drugs in Comparison Table: Tadalafil vs Sildenafil vs Vardenafil vs Avanafil

ED drugs in Comparison Table: Viagra vs Cialis vs Levitra vs Stendra
Brandname Viagra Cialis Levitra Stendra *
Active ingredient Sildenafil Tadalafil Vardenafil Avanafil *
Drugs Class & Mode of action All these drugs are used by men who experience problems with erection. As all PDE5 inhibitors, they avert phosphodiesterase-5 from elimination of cyclic guanosine monophosphate (cGMP) so that cGMP acts much longer
Names of generics Kamagra, Caverta, Eriacta, Intagra Apcalis Oral Jelly, Tazalis, Tadalista, Tadalista Soft Vilitra, Filitra, Filitra Soft, Filitra Oral Jelly Avana
Outset of action In 45 minutes after intake In 30 minutes after intake In 30 minutes after intake In 30-45 minutes after intake
Biological half-life(duration of action) 36 hours 4-6 hours 4-5 hours 5 hours
Available dosage 2.5mg, 5mg, 10mg, 20mg, 40mg, 60mg, 80mg 25mg, 50mg, 100mg, 120mg, 130mg, 150mg, 200mg 10mg, 20mg, 40mg, 60mg, 80mg 50mg, 100mg
Available analogs for women Femalefil Womenra, Femigra, Vilagra, Lovegra, Ladygra - -
Side effects light headache, muscle or back pains, abdominal discomfort or pain, burping, acid reflux, tachycardia, facial edema vertigo, problems vision and hearing, flushing, headache, abdominal pain, flushing, indigestion, nasal congestion, photophobia, blurred vision, seeing everything tinted blue (cyanopsia), loss of peripheral vision, colorblindness, vision impairment in rare cases, noise in ears light headache, gastrointestinal problems, heart attack, stroke, nausea, problems vision and hearing, arthralgia, myalgia, rash, itch, priapism fever, muscle spasms, redness of the face, neck, arms, rarely - upper chest, sore throat, runny nose
Interaction with other drugs Not recommended for use along with: Nitrates, other PDE5 inhibitors, antibiotics, antivirals, antufungal drugs Not recommended for use along with: GC stimulator, other PDE5 inhibitors Not recommended for use along with: phenylalanine, sorbitol Not recommended for use along with: Nitrates, Alpha-Blockers, CYP3A4 Inhibitors
Interaction with food and drinks Products with high glucose content may worsen the drug effect. You can eat any food or drink even alcohol but not too much. Fatty Foods, sour and sweet drinks (especially orange and grape juice), alcohol reduce the drug effect. It is recommended to take drug on empty stomach. Avoid grapefruit juice as it leads too less effectiveness of the drug It starts acting in 1.30 hour after fatty food. The intake of alcohol is acceptable but not in large amounts. Same rules with orange and grapefruit.
Contraindications The drug is not recommended for:1) patients with cardiovascular disease,2) those with left ventricular outflow obstruction,3) those who experience blood pressure problems. The drug is not recommended for:1) patients with decreased liver function2) patients with severe renal failure3) patients with low blood pressure4) those who recently experience stroke or heart attack5) men with genetically-inherited retinal problems The drug is not recommended for:1) patients with fructose intolerance.2) patients who had a heart attack or stroke 6 month before The drug is not recommended for:1) patients with certain serious cardiovascular or blood pressure problems , 2) men who have severe liver or kidney failure, 3) those who have vision problems.
Excretion (Clearance) Feces (>60%), urine (>30%) Fecal (>80%) and renal (>13%) Feces (>95% as metabolites); urine (>6%) Feces (>62%); urine (>21%)

Avanafil

Avana - a comparatively new medicine, demonstrating relatively great progress in treatment of erectile dysfunction, which is based on the same principle of functioning as the famous Viagra, Cialis and Levitra. Being a phosphodiesterase-5 inhibitor it provides stable erection for 4 to 6 hours after taking the pill. This medication is distributed under the trade name Stendra and Spedra, and already has a range of very resultful and low-cost generics, mostly from Indian manufactures, like Sunrise Remedies Pvt. Ltd.

This drug is claimed to be more effective or safe for some men. Its basic component is avanafil, which was approved by the FDA (Food and Drug Administration) in 2012.The main advantages of the drug consist in more rapid activation time, and perhaps in a shorter list of adverse effects. In fact, in a review, patients reported onset of effect within 15-20min after the intake. The most popular dosage is 100mg of avanafil per tablet, but there have been some combined medicines invented by Indian pharmacists, these are: top avana, super avana and extra super avana. Top avana contains 50 mg of avanafil and 30 mg of dapoxitine for prolongation of erection. Super avana consists of 60 mg of avanafil and 100 mg of dapoxetine, which provides relatively prolonged sex and the onset of action starts already in 15 minutes. Extra super avana is a remedy with 200 mg of avanafil plus 60 mg of dapoxitine, these dosages will cure potency much effectively staying completely safe for your general health.

Benefits of Stendra (Avanafil)

In comparison to Viagra, the improved formula of Stendra allows you to keep the erection longer, therefore increasing the duration of sexual intercourse. The advantage of Stendra in front of Viagra is that it can be consumed with moderate doses of alcohol (for example, up to 300 ml of whiskey or 3 glasses of wine), as well as along with fatty foods or sour drinks, whereas it is recommended to take Viagra on an empty stomach, for a better effect. Another indisputable advantage of Stendra in comparison to other PDE-5 inhibitors - is less likelihood of occurring side effects, especially if all the instructions are followed.

the One of reviews:
To be honest, I used to think Viagra was total BS before I got ed myself. I thought my life was over, my wife would leave me and all that but it's been 3 years since I got the first symptoms and I couldn't care less. Well, it took some time to get adjusted to the reduced sensitivity and all, my PA even got me on Cialis daily instead but that would keep me dizzy all day every day. So I just went from 50 mg to 25 mg and that solved the problem. I'm as stiff as ever and with no side effects at all. Feels awesome!

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